protein synthesis inhibitors mechanism of action

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rRNA Binding Sites and the Molecular Mechanism of Action ... - NCBI。

2016年7月22日 · More specifically, they are believed to inhibit translation by binding to the 16S rRNA and inhibiting the binding of aminoacyl-tRNA to the mRNA- ...： tw | tw。

Inhibitors of protein synthesis identified by a high throughput ... - NCBI。

The mechanism of action of baccharinol has not been reported, but it is a trichothecin epoxide that likely inhibits elongation. Compounds were titrated into 96- ...。

Erythromycin- and Chloramphenicol-Induced Ribosomal Assembly ...。

Several protein synthesis inhibitors are known to inhibit ribosome assembly. ... Prediction of mechanisms of action of antibacterial compounds by gene ...。

Molecular mechanism of viomycin inhibition of peptide elongation in ...。

2016年1月26日 · It inhibits bacterial protein synthesis by blocking elongation factor G ... We constructed a quantitative model for viomycin action with ...。

Translation inhibitors induce cell death by multiple mechanisms and ...。

2012年10月11日 · One such inhibitor is homoharringtonine (HHT; Omacetaxine mepesuccinate), which inhibits translation elongation by hindering the peptidyl ...。

Application to TRAIL Sensitization by Protein Synthesis Inhibitors。

2016年10月21日 · Therefore, such an assay was developed, based on puromycin incorporation into nascent polypeptides and quantitation by the ICW method. This was ...。

A Novel Combination Approach Targeting an Enhanced Protein ...。

2020年6月1日 · Together, our findings demonstrated that dual inhibition of MYC (transcription) and mTOR (translation) of the protein synthesis pathway can ...。

Cordycepin Inhibits Protein Synthesis and Cell Adhesion through ...。

2009年9月29日 · Inhibition of AMPK prevented translation repression by cordycepin and abolished 4EBP1 dephosphorylation, indi- cating that the effect of ...。

Escherichia coli K-12 substr. MG1655 rrsG-gltW-rrlG-rrfG - Trypanocyc。

Key to regulator colors: Green: activator; Magenta: inhibitor; Brown: dual; Gray: unspecified. A dashed outline for a transcription factor binding site or a ...。

The translation inhibitor cycloheximide affects ribosome profiling ...。

2019年8月24日 · CHX is a small molecule that inhibits translation elongation by binding to ... Furthermore, the effect of CHX on ribosome profiling has been ...

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